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Side Effects: Postural hypotension, diarrhea (from increased GI motility), impaired ejaculation Pharmacokinetics: Guanethidine is too polar to enter into the CNS, and hence has little or no CNS side effects

This matters because glutathione supports immune function, detoxification, and cellular repair

Do not use GHK-Cu Cream if you have an active cancer, or if you have had cancer within the last two years

According to FDA prescribing information, these effects are typically most pronounced during initial treatment and after dose escalations, often improving over time as the body adjusts