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Extracellular glutathione S-transferase omega-1, a cytosolic enzyme that modulates the S-thiolation status of intracellular factors involved in the inflammatory response, and its polymorphisms have been associated with an increased risk to develop COPD and could have a biological and clinical significance in cystic fibrosis (115)

The study authors suggest that understanding the drugs mechanism in the entire bodynot just the braincould open up avenues for treating alcohol use disorder

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