retatrutide triple agonist glp-1 gip glucagon phase 2 nejm 2023 vs Tirzepatide Compared Retatrutide, a TRIPLE agonist (GLP1,

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Characterization of serotonin and N-acetylserotonin systems in the human epidermis and skin cells

Analysis of real-world data compared patients on GIMOTI (n=51) to Oral Metoclopramide (n=41), both taking GLP-1s, showing significant statistical improvement for GIMOTI over Oral Metoclopramide in All Cause Emergency Department Visits (-91%, p=0.001), All Cause Office Visits (-41%, p=0.027) and All Cause Hospital Outpatient Visits (-89%, p=0.032) within 6-month index period Data presented at American College of Gastroenterology (ACG) 2024

To validate our analysis, we resorted to LC-MS to sensitively analyse the presence of cystathionine which is a key intermediate in the TS pathway