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2.20 Experimental design and statistical analysis considerations A preliminary finding that exendin-4-C16 shows reduced -arrestin-2 recruitment compared to exendin-4 (Lucey et al ., 2020), gave us a reasonable expectation that the two ligands would display alterations to other aspects of their pharmacology

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ICH E9 (R1) addendum on estimands and sensitivity analysis in clinical trials to the guideline on statistical principles for clinical trials

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J Exp Med, 167: 700-705

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