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In line with preclinical research, we find that ghrelin increases reward responses across studies in key nodes of the motivational circuit, such as the nucleus accumbens, pallidum, putamen, substantia nigra, ventral tegmental area, and the dorsal mid insula

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Notably, 17 human proteins were upregulated in the defense response to bacterium, including C4BPA, RNASE3, CTSG, MMP9, RETN, AZU1, EPX, MPO, ELANE, SERPINB4, PRTN3, LCN2, CRP, S100A9, S100A8, HNRNPA0, DEFA3, APCS, FGA, NT5C3A, HRG, F12, LTF, FGB, FGG, RTN4R, C1QA, C5, CFP, TTN, IGHG2, A2M, TF, PPP1CB, and CFH