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These timepoints were selected to represent distinct stages of iHLO development and maturation: Day 7 signifies the hepatoblast differentiation stage, Day 15 marks the early hepatocyte stage, and Day 30 and Day 45 indicate progressively matured liver organoid stages with increasing liver cell populations and functions

It helps the body turn fat into energy

Wilding et al., 2021), leading to this class of drugs being hailed as game changers for chronic weight management (Kolata, 2021)

In some embodiments, the auris formulations or compositions described herein are administered into the ear canal, or in the vestibule of the ear