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The observed plasma increase in adenosine could be due to a decrease in adenosine deaminase activity, inhibition of adenosine kinase, or an increase in 5-nucleotidase, all of which can occur in the presence of oxidative stress [7072]

Additional data have shown a correlation between diminished CD4+ T cell counts and increased levels of pro-inflammatory cytokines (IL-1, IL-17, and IL-6) that contribute to systemic inflammation, and malondialdehyde (MDA), which is an end-product of lipid-peroxidation and a marker for oxidative stress

Hepatic but not extrahepatic insulin clearance is lower in African American than in European American women

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