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Exposure to 3-BHA compromised the thermogenic capacity of the differentiated cells and promoted lipogenesis, evidenced by the increased intracellular lipid accumulation and elevated expression of pparg , perilipin , adiponectin , and fabp4 [213]

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J Inorg Organometal Polym Mater

Metabolic effects of GLP-1R agonismGIPR antagonism in DIO Per-Gipr KO mice Consistent with previous data showing that GIPR agonism acts in the CNS 15 to decrease food intake via GABAergic GIPR neurons 14 , we found that the inhibition of food intake following single subcutaneous (s.c.) administration of acyl-GIP (100 nmol kg 1 ) was fully preserved in DIO Per-Gipr KO mice (Fig