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Inhibition of gastric inhibitory polypeptide signaling prevents obesity
The effect of GLP- 1 together with GIP on food intake, body weight, and locomotor activity was determined following intracerebroventricular (ICV) administration of GLP- 1 and/or GIP in mice
In gastrectomized animals the application of the investigated agents (i.e., NaBPC157 or the reference agents before cysteamine) significantly prevented the otherwise severe duodenal lesion development noted in the control gastrectomized cysteamine rats
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