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Its core action involves downregulating pro-inflammatory cytokines (TNF-, IL-6, IL-1) via inhibition of NF-B, MAPK, and TLR signaling

They completed the following self-assessments at the beginning and end of the study: Eating Disorder Examination Questionnaire (EDE-Q) 70 , Eating Disorder Inventory-3 (EDI-3) 71,72 , Eating Disorder Clinical Impairment Assessment (CIA) 73 , Beck Depression Inventory 2 (BDI) 74 , Spielberger State-Trait Anxiety Inventory (STAI) 75 , and Temperament and Character Inventory (TCI) 76

Yes MTHFR A1298C reduces enzyme activity by approximately 20% in heterozygotes and more in compound heterozygotes (C677T + A1298C)

You might also experience blurred vision, nausea, or cold, clammy skin