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GLP-1 drugs damage the Vagus nerve causing denervation in the gut, which can result in permanent paralysis

It involves your nerves, your immune system, and the energy factories inside your cells called mitochondria

In diabetes mellitus, oxidative stress is increased and ROS are produced at an elevated rate, resulting in a cascade of events: reduced NO increased prothrombotic factors including tissue factor, and plasminogen activator inhibitor-1 increased endothelin-1, resulting in thrombosis and vasoconstriction, and increased nuclear factor kappaB and activation protein 1, which leads to ED [52]