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[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Rosenstock J., Frias J., Jastreboff A.M., et al

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This might occur if: The injection site was not properly cleaned before use The needle penetrated a superficial blood vessel Blood tracked back through the needle during injection Remember that tirzepatide auto-injectors are designed for single use only and should be discarded immediately after injection, regardless of whether medication appears to remain in the device

So, again, its literally such an amazing thing the way these things work in the central nervous system that if you dose them appropriately, you can absolutely dramatically transform your life