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In contrast, active targeting involves the use of specific ligands, antibodies, or other molecules on the surface of nanocarriers to bind to receptors or antigens that are uniquely expressed, or overexpressed, on target cells, allowing for precise delivery [66]

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These effects result from the peptide's ability to activate multiple growth factor pathways simultaneously, including TGF-, basic fibroblast growth factor (bFGF), and insulin-like growth factor-1 (IGF-1)