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3.11 Histopathology of hippocampus of rat brain The examination of a section of the cerebral cortex stained with hematoxylin and eosin (H&E) reveals several critical observations: (A) Cortical neurons () characterized by rounded vesicular nuclei (yellow ) display sharply demarcated nuclear contours, while blood vessels (v) are accompanied by a narrow perivascular space indicative of degenerated and shrunken neurons