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236 In addition, high dietary iron regulates the circadian rhythm of hepatic glycogen production through blood-mediated interactions between nuclear receptor subunit 1 group D member 1 and nuclear receptor auxiliary inhibitor 1

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One group developed a drug-eluting hydrogel system which, when implanted in a surgical resection site, has the benefits of delivering high doses of the drug directly to the target site, reducing systemic side effects, with continuous and sustained release (unlike intermittent doses with other drug delivery methods) (Brudno et al., 2018)