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The 4 mm needle is long enough to traverse the skin and reach the subcutaneous tissue with minimal risk of intramuscular or intradermal penetration
Far from being a single procedural step, a FIH trial is built on a broad body of scientific, regulatory and operational work designed to ensure that the transition from preclinical research to human investigation takes place within a rigorous framework focused on safety, quality and evidence generation
Proc Natl Acad Sci USA (2016) 113(34):E496675
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