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It may take several weeks for your body to adjust to semaglutide, especially as the dosage increases

In a 2025 observational cohort, the Risk of Vestibular Disorders with Semaglutide and Tirzepatide study reported dizziness in 18% of semaglutide users compared with 10% in the control group, indicating a higher-than-baseline incidence and reinforcing the need to monitor for dose- or timing-related patterns

It works by specifically targeting the anterior pituitary gland to promote the natural release of growth hormone, which can lead to increased fat metabolism and fat breakdown

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