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Hypothesis testing We hypothesize a positive effect of LC on crustacean pigmentation, through a series of potential interactions between LC and FA, and between FA and Axn to impact Axn distribution as CRCN-Axn complexes or Axn esters

We then monitor IGF-1 levels at regular intervals typically at 6 weeks, 3 months, and every 36 months thereafter to confirm the protocol is working and adjust dosing as needed

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2.2 Functional implications of specific gut microbiota in hypothyroidism As seen in the results mentioned above, Phascolarctobacterium is more abundant in patients with hypothyroidism (Liu et al., 2020)