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10.1016/j.bbabio.2010.03.001 75 MalkovA.IvanovA

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A 2015 meta-analysis evaluated information from studies about off-label TPM use for essential tremors

IDO-1 is found in various immune cells, including dendritic cells and macrophages, where it suppresses immune function by depleting tryptophan an amino acid vital for T-cell activity and generating immunosuppressive byproducts such as kynurenine