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Pramlintide suppresses inappropriate postprandial glucagon secretion from pancreatic alpha-cells, an effect that is impaired in diabetes and contributes significantly to postprandial hyperglycemia

GLP-1 receptor agonists slow gastric emptying (though less so at microdoses)

For example, there are medications that can reduce nausea

The 2013 AHA/ACC/TOS guidelines for the management of overweight and obesity in adults, published in Circulation, established clear clinical criteria for pharmacotherapy in patients with obesity, lending weight to the argument that anti-obesity medications like Wegovy are medically necessary rather than elective