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In addition to increasing PCSK1 , liraglutide treatment increases the relative abundance of other cellassociated genes in the same subcluster of cells
If you want a measurable baseline rather than an empirical 812 week titration trial, the PlexusDx Precision Peptide Genetic Test ($99 add-on after month one) profiles 49 genes and 58 variants relevant to GLP-1 response
47 , 48 , 49 , 50 , 51 An early study of MC1R variants in humans by Valverde et al reported an association of specific variants with red hair colour, fair skin and impaired tanning response to UV radiation, with MC1R variants identified in 82% of patients with red hair