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The most commonly reported side effects in clinical trials are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, which are typically most pronounced during the dose titration phase and tend to improve over time

Ann Intern Med 165:305315 Idilman R, Mizrak D, Corapcioglu D et al (2008) Clinical trial: insulin-sensitizing agents may reduce consequences of insulin resistance in individuals with non-alcoholic steatohepatitis

Peptide Sequence: Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1) Molecular Formula: CHNO Molecular Weight: 1024.198 g/mol PubChem CID: 92432 CAS Number: 121062-08-6 Source: PubChem In laboratory models, MTII may be used to investigate melanocortin receptor activity, signal transduction, and pigment-pathway responses