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For the evidence behind each natural compound, see natural GLP-1 foods and supplements

A novel GLP-1/GIP dual agonist is more effective than liraglutide in reducing inflammation and enhancing GDNF release in the MPTP mouse model of Parkinsons disease

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Case in point: a 2013 review supported growth hormone therapy as a treatment for patients with cognitive impairment, theorizing that growth hormone may interact with receptors in the central nervous system associated with learning and memory.20 Another case in point: a 2018 review found that IGF-1 plays a major role in adult brain function and decreases with age, a decrease that seems to precede cognitive decline in the elderly.21 To tie this all together, we can point to a 2012 clinical trial directly examining the effects of tesamorelin on cognitive function