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Mechanistically, SGLT2 inhibitors act predominantly through hemodynamic and cardiorenal pathways, whereas GLP-1 receptor agonists exert metabolic, anti-inflammatory, and anti-atherosclerotic effects, providing a rationale for potential complementarity

Emerging clinical trials are exploring the efficacy of GLP-1 drugs in treating conditions such as: Cardiovascular Disease (CVD): Given the high prevalence of CVD in China, there is significant interest in using GLP-1 drugs to reduce cardiovascular risk in patients with obesity and diabetes

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However, one important factor often overlooked is staying properly hydrated