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Follow the instructions for your medication and do not use heat to warm the pen

As with other incretin receptor agonists, the most frequently reported side effects of retatrutide in clinical trials were gastrointestinal in nature , and were most pronounced during the dose escalation phase

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The concomitant improvement in insulin sensitivity and beta-cell function, which were associated with normalization of glucose levels in people with prediabetes, suggests that tirzepatide treatment may delay and potentially halt progression to T2D, by inducing so-called beta-cell rest and ultimately, modifying the natural history of prediabetes/T2D