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Areas of investigation include: nitric oxide signaling pathways endothelial cell migration and angiogenesis fibroblast proliferation extracellular matrix remodeling inflammatory response modulation These mechanisms are commonly studied in experimental models involving connective tissue recovery and vascular repair responses

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Sever et al., 2019), thus avoiding and directly counteracting VEGF tumorigenesis (Radeljak et al., 2004)

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