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Mechanism Selective NNMT inhibition, proposed to preserve intracellular NAD+/SAM and reduce fat-cell lipogenesis demonstrated in mice, not humans

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Left untreated, a B12 deficiency can also lead to long-term health issues

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Study 5: Phase 2b clinical study, failure in obesity Citation: Metabolic Pharmaceuticals Phase 2b trial (2007), not fully published

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