Despite consuming similar quantities of food, the mice that received milk thistle lost about 5% of their weight, while the control group continued gaining weight throughout the study ( A handful of small human studies have evaluated milk thistles effects on certain metabolic symptoms associated with obesity, such as insulin resistance and inflammation, but none have looked specifically at milk thistles ability to promote fat loss ( Although the results are promising, a single animal study does not constitute enough evidence to reliably determine whether milk thistle can aid weight loss in humans

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