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Still, they are also a result of mitochondrial dysfunction, which occurs when mitochondria lose the protection of GSH, free radicals attack the mitochondria, and cellular energy decreases.8 Autoimmune conditions like multiple sclerosis, Crohns disease, rheumatoid arthritis, diabetes, Lyme disease, heavy metal load, organotoxins, and more all have mitochondrial dysfunction, low levels of GSH, and profound fatigue

Topical formulations are common for surface skin concerns, while supervised injectable or compounded protocols may be considered for broader regenerative goals

Mitochondrial F 0 /F 1 ATPase subunit has been shown to be glutathionylated by GSTO1 (ref

First to go was glutamate aka MSG following the principles of the Reduced Excitatory Inflammatory Diet (REID references can be found here ) developed by PhD biochemist Dr Katherine Reid