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The Primary Care Dermatology Society (PCDS) and NHS UK provide further guidance on the assessment of diffuse hair loss

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Considerations when switching Currently, there is no NICE or Medicines and Healthcare products Regulatory Agency guidance that specifies how to switch between tirzepatide and semaglutide

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A 2023 study in Obesity reinforced this, noting that participants on GLP-1s lost significant amounts of fat-free mass if they were not concurrently engaging in resistance training or consuming sufficient dietary protein

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NICE guidance (NG28) recommends their use in specific clinical scenarios, often as part of a stepwise approach to diabetes management

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