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Nevertheless, pathways implicated in preclinical studies, including angiogenesis, inflammatory modulation, and collagen remodeling, intersect with biologic systems central to incision healing and complication avoidance, although these mechanistic signals have not been shown to translate into improved clinical outcomes

The type and complement of these protective systems can vary significantly, both between tissues and between organisms

These compounds have shown remarkable potential in accelerating healing, reducing inflammation, and promoting tissue repair in horses