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NIH ODS Fact Sheet for Health Professionals: Vitamin B12 (updated 2024)

Possible Symptoms Fatigue, weakness, reduced exercise tolerance, or shortness of breath Pale or yellow-tinged skin A sore, smooth, or inflamed tongue Numbness, tingling, burning, or altered sensation in the hands or feet Balance problems, unsteady walking, or reduced coordination Memory difficulty, concentration changes, confusion, or mood symptoms Palpitations related to anemia Unexplained weight loss or appetite changes Do not delay care for neurologic symptoms New numbness, weakness, walking difficulty, balance loss, confusion, vision change, or bowel/bladder neurologic symptoms require prompt medical evaluation

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