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SCC or BCC expands as a precancerous lesion named actinic keratosis, which is also called keratinocyte intraepidermal neoplasia, very general in UV-exposed regions and looks like reddish macules which are further enfolded by yellowish scales

Endoplasmic reticulum stress is a state in which the accumulation of unfolded/misfolded proteins is accelerated after ER disorders caused by a variety of physiological and pathological conditions

The presence of furin cleavage site in diphtheria toxin (R-V-R-R ) and Pseudomonas exotoxin A (R-Q-P-R ), enhances their cytotoxic spectrum 339,340

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