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Current research directions include investigations into glutathione's potential roles in neurodegenerative disease prevention and progression, cardiovascular disease risk modification, metabolic syndrome and diabetes management, cancer prevention and potentially as adjunct to certain cancer therapies, liver disease including fatty liver and cirrhosis, respiratory conditions including COPD and asthma, autoimmune and inflammatory conditions, and healthy aging and longevity optimization

Further, these studies have concurrently indicated that the increase of the serum selenium status leads to the corresponding increase of plasma GPx level up to a threshold and beyond that GPx activity is saturated with no further increase irrespective of the selenium status

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