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By week four of uninterrupted use, melanocyte MC1R density can drop by 3040%, requiring progressively higher doses to achieve the same tanning response

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At the starting dose of 2.5mg per week, a 10mg vial lasts four weeks

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Expect screening for labeled contraindications, including personal or family history of medullary thyroid carcinoma and Multiple Endocrine Neoplasia syndrome type 2, and expect questions about pancreatitis, gallbladder disease, retinopathy, gastroparesis and pregnancy

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