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The resulting oxaloacetate can be used to fill up (anaplerosis) the TCA cycle or diverted into the gluconeogenic pathway to glucose

Chapter 11: Undertaking network meta-analyses

Side Effect Profile Both medications have similar side effect profiles, with gastrointestinal issues being the most common: Nausea Diarrhea Vomiting Constipation Abdominal pain While the incidence of side effects is generally similar between the two medications, some studies suggest that tirzepatide may have a slightly higher rate of gastrointestinal side effects, particularly at higher doses

Systolic pressure (the top number) measures force during heart contraction, while diastolic pressure (the bottom number) reflects force between heartbeats