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Research has shown that Xuebijing can induce ferroptosis in CCR2 hi monocytes by activating the Nrf2/HO-1 axis and inhibiting GPX4 expression, thereby suppressing the proinflammatory response and M1 polarization of these cells, reducing their infiltration into lungs, and ultimately alleviating sepsis-associated acute lung injury (Yang et al., 2025)

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One study evaluated the association between statin use and efferocytosis, an inflammation-resolving process involved in recovery from pneumonia, in 22 community-acquired pneumonia patients in London