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In this systematic review, Bhandari et al

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These astrocytic end-feet may also present a swollen phenotype under certain pathological conditions [46, 57]

SMR insights into the causal relationship between GLP-1RA and DR In the SMR analysis between blood GLP-1R target gene expression and DR risk, we visualised the SNP distribution and P -value relationship between the eQTL dataset and the GWAS dataset for DR, where the labelled dots are the instrumental variable top-SNPs (usually those with the smallest P -value in the exposure dataset), and the red line represents P = 0.025, above which indicates significant statistical significance, while the opposite does not suggest a significant cause-and-effect relation between exposure and outcome (Fig