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GCGR signaling in hepatocytes activates adenylyl cyclase, increasing cAMP and driving glycogenolysis, gluconeogenesis, and critically, hepatic fatty acid oxidation via CPT1a upregulation

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A meta-analysis of 13,275 patients further supports that SGLT2i therapy significantly reduces the risk of hospitalisation and all-cause mortality [22]

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L-carnitine: the transporter idea L-carnitine is not a fat itself

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Insulin glargine was given to female rats before mating, during mating, and throughout pregnancy at doses up to 0.36 mg/kg/day, which is approximately 50 times the recommended human subcutaneous starting dosage of 0.2 units/kg/day (0.007 mg/kg/day), on a mg/kg basis

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