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In this Review, we summarize the data from CVOTs of GLP1R agonists in patients with T2DM and describe the actions of GLP1R agonists on the heart and blood vessels

Their primary mechanism involves reducing circulating cholesterol, binding to LDL particles, and enhancing systemic antioxidant activity (Ahmadi et al., 2022)

In vivo, treated mice showed significantly reduced body weights, white adipose masses, and adipocyte sizes findings replicated across multiple independent studies from the same research group

This effect may be particularly helpful for individuals aiming to maintain healthy blood pressure levels and support overall cardiovascular health