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SUMMIT (NCT04847557) es un ensayo clnico de fase 3, multicntrico, aleatorizado, doble ciego, paralelo y controlado con placebo, que compar la eficacia y la seguridad de tirzepatida con placebo en adultos con insuficiencia cardaca con fraccin de eyeccin preservada (ICFEp) y obesidad, con o sin diabetes tipo 2

In the TME, DCs play a key role in capturing, processing, and presenting tumor-associated antigens, as well as providing co-stimulation and soluble factors to regulate T-cell responses (70)

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For example, if genetic testing reveals you carry variants linked to slower GLP-1R signaling, your prescriber may recommend a slower dose titration schedule to give your thyroid absorption time to stabilize at each level