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Now, researchers are looking at pairing these glucagon-like peptide 1 ( GLP 1 ) agonistsand dual GLP-1/ glucose-dependent insulinotropic polypeptide (GIP) receptor agonists with drugs that treat inflammatory diseases such as psoriasis to see if the combination boosts effectiveness

"The only way to potentially avoid the weight rebound is to taper the GLP-1 slowly, while continuing other rigorous behavioral programs and lifestyle interventions, including diet and exercise," says Dr

A, Diagram of the proglucagon gene and encoded mRNA

For enhanced effectiveness, GLP-1 therapy is integrated with personalized lifestyle modifications