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Dehydration from reduced food and fluid intake, changes in electrolyte balance, and shifts in sleep quality can amplify low-energy sensations

The percentage of patients who achieved a clinically meaningful treatment response (defined as achieving at least 5% weight loss after 1 year of treatment) ranged from 36% to 57% with CONTRAVE, compared to 17% to 43% with placebo

If you bruise frequently at injection sites, try applying ice before injection to numb the area, rotating sites more consistently, and injecting more slowly

However, real-world evidence beyond prospective settings is needed to assess the impact of semaglutide in routine clinical practice, where monitoring frequency may vary