While most people experience few side effects when taking glutathione, one possible adverse effect is an upset stomach if taken in high doses
Since NACA is not approved for use in humans, a related drug, N-acetylcysteine (NAC), was used
Cancer Metab 1(1):7 Avolio R, Swann Matassa D, Criscuolo D, Landriscina M, Esposito F (2020) Modulation of mitochondrial metabolic reprogramming and oxidative stress to overcome chemoresistance in cancer
For example, studies using rodents and primary neuron cultures have demonstrated that sulforaphane upregulates key antioxidant enzymes, such as glutathione-S-transferase (GST), NAD(P)H oxidoreductase 1 (NQO1), and heme oxygenase-1 (HO-1), leading to reduced oxidative burden in both neurodevelopmental and neurodegenerative models (Innamorato et al., 2008