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Lipid effects of glucagon-like peptide 1 receptor analogs

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Acetyl-carnitine is more easily absorbed from the gut, crosses the blood-brain barrier more readily, and as a bonus supplies acetate, which may boost mitochondrial metabolism both for energy and acetylcholine production

At the same time, both diarrhea and constipation are common side effects of GLP-1 analogs (36, 37), indicating a complex mechanism at play