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In addition to the changes in energy metabolism during transition in dairy cows, various studies also confirmed endocrine, hematological and immunological changes ( A better understanding of temporal hematologic changes and of the impairment of leukocyte function around parturition may be important to enhance recovery, stabilize immunologic responses, and improve energy metabolism in cows

SIBO is formally defined as a bacterial population in the small intestine exceeding 1010 colony-forming units (CFU) per milliliter, though the exact diagnostic threshold remains debated

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