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Because it can help thin and loosen mucus while also influencing oxidative stress and inflammation, it has been studied extensively in chronic bronchitis and COPD.1 12 A 2015 meta-analysis found that NAC reduced exacerbations in people with chronic bronchitis and COPD, though more recent research suggests benefits may vary depending on the patient population and dose used.1 22 Women with PCOS or insulin-resistance concerns NAC has become one of the more widely studied supplements for PCOS

These encompass nuclear hormone receptor agonists, fibroblast growth factors 19 and 21, incretins (single, dual, or triple), sodium-glucose cotransporter inhibitors, and agents modulating metabolic pathways

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