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It also performs a dual action that distinguishes it from simple collagen-boosting ingredients: it upregulates the matrix metalloproteinases (MMP-1 and MMP-2) that clear damaged collagen, while simultaneously upregulating tissue inhibitors (TIMP-1) that prevent excessive degradation [3]

The amount of medication to be taken follows the first verb of the SIG, which tells the patient how the medication is to be consumed

Call 911 or proceed to the nearest emergency department immediately if experiencing: chest pain or pressure lasting more than a few minutes or that resolves and returns

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