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Small but measurable differences in fat mass often show up after about 8 to 12 weeks of consistent supplementation, with clearer results by 12 to 24 weeks

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(45) demonstrated that eight sessions of OFA (650 nm, 10 mW) over four weeks compared to a 20 mW regimen, targeting GB34 and Xuanzhong acupoint (GB39) for three minutes per point, following intervention, cartilage degeneration and proteoglycan content were assessed via carmine staining