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In addition, licorice root extract (123) and modified Si Jun Zi Tang (124) have been demonstrated, in both in vitro and in vivo studies, to regulate multiple metabolic pathways, including glycolysis and glutamine, serine, and glycine-related metabolism, thereby influencing cancer cell proliferation, apoptosis, and migration

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We suggest that a possible explanation for the lack of effect of ghrelin on insulin in this study may be a result of the stimulatory actions of GLP-1 masking the inhibitory effect of ghrelin on the beta cell